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Dynein–Dynactin–NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble
To position the mitotic spindle within the cell, dynamic plus ends of astral microtubules are pulled by membrane-associated cortical force-generating machinery. However, in contrast to the chromosome-bound kinetochore structure, how the diffusion-prone cortical machinery is organized to generate lar...
Autores principales: | Okumura, Masako, Natsume, Toyoaki, Kanemaki, Masato T, Kiyomitsu, Tomomi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037482/ https://www.ncbi.nlm.nih.gov/pubmed/29848445 http://dx.doi.org/10.7554/eLife.36559 |
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