Serial integration of Dean-structured sample cores with linear inertial focussing for enhanced particle and cell sorting

In this contribution, a channel aspect ratio of >2 was used to access high velocity regimes to provide confined sample cores by Dean focussing in advance of linear inertial focussing. This produces a singular separation origin with a mirrored transport path for efficient particle and blood cell s...

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Detalles Bibliográficos
Autores principales: Holloway, Paul M., Butement, Jonathan, Hegde, Manjunath, West, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2018
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037536/
https://www.ncbi.nlm.nih.gov/pubmed/30034567
http://dx.doi.org/10.1063/1.5038965
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author Holloway, Paul M.
Butement, Jonathan
Hegde, Manjunath
West, Jonathan
author_facet Holloway, Paul M.
Butement, Jonathan
Hegde, Manjunath
West, Jonathan
author_sort Holloway, Paul M.
collection PubMed
description In this contribution, a channel aspect ratio of >2 was used to access high velocity regimes to provide confined sample cores by Dean focussing in advance of linear inertial focussing. This produces a singular separation origin with a mirrored transport path for efficient particle and blood cell sorting, while also increasing the spatial resolution for multiscale sorting.
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spelling pubmed-60375362018-07-20 Serial integration of Dean-structured sample cores with linear inertial focussing for enhanced particle and cell sorting Holloway, Paul M. Butement, Jonathan Hegde, Manjunath West, Jonathan Biomicrofluidics Regular Articles In this contribution, a channel aspect ratio of >2 was used to access high velocity regimes to provide confined sample cores by Dean focussing in advance of linear inertial focussing. This produces a singular separation origin with a mirrored transport path for efficient particle and blood cell sorting, while also increasing the spatial resolution for multiscale sorting. AIP Publishing LLC 2018-07-09 /pmc/articles/PMC6037536/ /pubmed/30034567 http://dx.doi.org/10.1063/1.5038965 Text en © 2018 Author(s). 1932-1058/2018/12(4)/044104/12 All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Regular Articles
Holloway, Paul M.
Butement, Jonathan
Hegde, Manjunath
West, Jonathan
Serial integration of Dean-structured sample cores with linear inertial focussing for enhanced particle and cell sorting
title Serial integration of Dean-structured sample cores with linear inertial focussing for enhanced particle and cell sorting
title_full Serial integration of Dean-structured sample cores with linear inertial focussing for enhanced particle and cell sorting
title_fullStr Serial integration of Dean-structured sample cores with linear inertial focussing for enhanced particle and cell sorting
title_full_unstemmed Serial integration of Dean-structured sample cores with linear inertial focussing for enhanced particle and cell sorting
title_short Serial integration of Dean-structured sample cores with linear inertial focussing for enhanced particle and cell sorting
title_sort serial integration of dean-structured sample cores with linear inertial focussing for enhanced particle and cell sorting
topic Regular Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037536/
https://www.ncbi.nlm.nih.gov/pubmed/30034567
http://dx.doi.org/10.1063/1.5038965
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