Tumor necrosis factor- and interleukin-6-producing high-grade B-cell lymphoma, not otherwise specified in the pleura

A 65-year-old man was admitted to our hospital with left-sided chest and back pain and dyspnea. Computed tomography demonstrated a marked circumferential left pleural thickening. A thoracoscopic pleural biopsy led to a diagnosis of high-grade B-cell lymphoma, not otherwise specified (HGBL, NOS). Lym...

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Autores principales: Nakayama, Shoko, Matsuda, Mitsuhiro, Adachi, Tatsuya, Sueda, Sanae, Ueda, Kayo, Kawahara, Kunimitsu, Ohashi, Yuka, Awaji, Sumie, Hashimoto, Shigeo, Matsumura, Itaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037664/
https://www.ncbi.nlm.nih.gov/pubmed/29998057
http://dx.doi.org/10.1016/j.lrr.2018.06.001
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author Nakayama, Shoko
Matsuda, Mitsuhiro
Adachi, Tatsuya
Sueda, Sanae
Ueda, Kayo
Kawahara, Kunimitsu
Ohashi, Yuka
Awaji, Sumie
Hashimoto, Shigeo
Matsumura, Itaru
author_facet Nakayama, Shoko
Matsuda, Mitsuhiro
Adachi, Tatsuya
Sueda, Sanae
Ueda, Kayo
Kawahara, Kunimitsu
Ohashi, Yuka
Awaji, Sumie
Hashimoto, Shigeo
Matsumura, Itaru
author_sort Nakayama, Shoko
collection PubMed
description A 65-year-old man was admitted to our hospital with left-sided chest and back pain and dyspnea. Computed tomography demonstrated a marked circumferential left pleural thickening. A thoracoscopic pleural biopsy led to a diagnosis of high-grade B-cell lymphoma, not otherwise specified (HGBL, NOS). Lymphoma cells were positive for tumor necrosis factor (TNF) and interleukin-6. This is the first case report of TNF- and IL-6-producing aggressive HGBL, NOS in the pleura, in which radiological findings mimicked pleural mesothelioma. The aggressive tumor progression in the present case may have been caused by abnormal cytokine production from lymphoma cells.
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spelling pubmed-60376642018-07-11 Tumor necrosis factor- and interleukin-6-producing high-grade B-cell lymphoma, not otherwise specified in the pleura Nakayama, Shoko Matsuda, Mitsuhiro Adachi, Tatsuya Sueda, Sanae Ueda, Kayo Kawahara, Kunimitsu Ohashi, Yuka Awaji, Sumie Hashimoto, Shigeo Matsumura, Itaru Leuk Res Rep Article A 65-year-old man was admitted to our hospital with left-sided chest and back pain and dyspnea. Computed tomography demonstrated a marked circumferential left pleural thickening. A thoracoscopic pleural biopsy led to a diagnosis of high-grade B-cell lymphoma, not otherwise specified (HGBL, NOS). Lymphoma cells were positive for tumor necrosis factor (TNF) and interleukin-6. This is the first case report of TNF- and IL-6-producing aggressive HGBL, NOS in the pleura, in which radiological findings mimicked pleural mesothelioma. The aggressive tumor progression in the present case may have been caused by abnormal cytokine production from lymphoma cells. Elsevier 2018-06-28 /pmc/articles/PMC6037664/ /pubmed/29998057 http://dx.doi.org/10.1016/j.lrr.2018.06.001 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Nakayama, Shoko
Matsuda, Mitsuhiro
Adachi, Tatsuya
Sueda, Sanae
Ueda, Kayo
Kawahara, Kunimitsu
Ohashi, Yuka
Awaji, Sumie
Hashimoto, Shigeo
Matsumura, Itaru
Tumor necrosis factor- and interleukin-6-producing high-grade B-cell lymphoma, not otherwise specified in the pleura
title Tumor necrosis factor- and interleukin-6-producing high-grade B-cell lymphoma, not otherwise specified in the pleura
title_full Tumor necrosis factor- and interleukin-6-producing high-grade B-cell lymphoma, not otherwise specified in the pleura
title_fullStr Tumor necrosis factor- and interleukin-6-producing high-grade B-cell lymphoma, not otherwise specified in the pleura
title_full_unstemmed Tumor necrosis factor- and interleukin-6-producing high-grade B-cell lymphoma, not otherwise specified in the pleura
title_short Tumor necrosis factor- and interleukin-6-producing high-grade B-cell lymphoma, not otherwise specified in the pleura
title_sort tumor necrosis factor- and interleukin-6-producing high-grade b-cell lymphoma, not otherwise specified in the pleura
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037664/
https://www.ncbi.nlm.nih.gov/pubmed/29998057
http://dx.doi.org/10.1016/j.lrr.2018.06.001
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