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Knockdown Indian Hedgehog (Ihh) does not delay Fibular Fracture Healing in genetic deleted Ihh mice and pharmaceutical inhibited Ihh Mice

The objective of this study was to determine if Ihh is required for fracture healing. Fibular fracture was created in adult Col2a1-CreER(T2); Ihh(fl)(/)(fl) mice. Ihh(fl)(/)(fl) mice received Tamoxifen (TM) to delete Ihh. WT mice received Cyclopamine to inhibit Hh pathway. Callus tissue properties a...

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Detalles Bibliográficos
Autores principales:	Li, Shengchun, Xiang, Chuan, Wei, Xiaochun, Li, Hongbin, Li, Kai, Sun, Xiaojuan, Wang, Shaowei, Zhang, Min, Deng, Jin, Wang, Xiaodu, Li, Pengcui, Li, Ruifang, Zhang, Yanxiang, Wei, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037729/ https://www.ncbi.nlm.nih.gov/pubmed/29985470 http://dx.doi.org/10.1038/s41598-018-28657-7

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