Subclonal mutation selection in mouse lymphomagenesis identifies known cancer loci and suggests novel candidates

Determining whether recurrent but rare cancer mutations are bona fide driver mutations remains a bottleneck in cancer research. Here we present the most comprehensive analysis of murine leukemia virus-driven lymphomagenesis produced to date, sequencing 700,000 mutations from >500 malignancies col...

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Detalles Bibliográficos
Autores principales: Webster, Philip, Dawes, Joanna C., Dewchand, Hamlata, Takacs, Katalin, Iadarola, Barbara, Bolt, Bruce J., Caceres, Juan J., Kaczor, Jakub, Dharmalingam, Gopuraja, Dore, Marian, Game, Laurence, Adejumo, Thomas, Elliott, James, Naresh, Kikkeri, Karimi, Mohammad, Rekopoulou, Katerina, Tan, Ge, Paccanaro, Alberto, Uren, Anthony G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037733/
https://www.ncbi.nlm.nih.gov/pubmed/29985390
http://dx.doi.org/10.1038/s41467-018-05069-9

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