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Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells

Glutathione (GSH) protects against oxidative damage in many tissues, including retinal pigment epithelium (RPE). Oxidative stress-mediated senescence and death of RPE and subsequent death of photoreceptors have been observed in age-related macular degeneration (AMD). Although the consequences of GSH...

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Detalles Bibliográficos
Autores principales:	Sun, Yun, Zheng, Yingfeng, Wang, Chunxiao, Liu, Yizhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037763/ https://www.ncbi.nlm.nih.gov/pubmed/29988039 http://dx.doi.org/10.1038/s41419-018-0794-4

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