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Cisplatin-activated PAI-1 secretion in the cancer-associated fibroblasts with paracrine effects promoting esophageal squamous cell carcinoma progression and causing chemoresistance

Preoperative chemotherapy is a promising strategy for the treatment of esophageal squamous cell carcinoma (ESCC). Acquired resistance to chemotherapy is a major obstacle in improving patient prognosis. Cancer-associated fibroblasts (CAFs) are the primary components of the tumor microenvironment and...

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Detalles Bibliográficos
Autores principales:	Che, Yun, Wang, Jingnan, Li, Yuan, Lu, Zhiliang, Huang, Jianbing, Sun, Shouguo, Mao, Shuangshuang, Lei, Yuanyuan, Zang, Ruochuan, Sun, Nan, He, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037765/ https://www.ncbi.nlm.nih.gov/pubmed/29988148 http://dx.doi.org/10.1038/s41419-018-0808-2

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