Coordinated autophagy modulation overcomes glioblastoma chemoresistance through disruption of mitochondrial bioenergetics

Glioblastoma Multiforme (GBM) is known to be one of the most malignant and aggressive forms of brain cancer due to its resistance to chemotherapy. Recently, GBM was found to not only utilise both oxidative phosphorylation (OXPHOS) and aerobic glycolysis, but also depend on the bulk protein degradati...

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Detalles Bibliográficos
Autores principales: Kriel, Jurgen, Müller-Nedebock, Kristian, Maarman, Gerald, Mbizana, Siyasanga, Ojuka, Edward, Klumperman, Bert, Loos, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037778/
https://www.ncbi.nlm.nih.gov/pubmed/29985441
http://dx.doi.org/10.1038/s41598-018-28590-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037778/
https://www.ncbi.nlm.nih.gov/pubmed/29985441
http://dx.doi.org/10.1038/s41598-018-28590-9

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