β-barrel Oligomers as Common Intermediates of Peptides Self-Assembling into Cross-β Aggregates

Oligomers populated during the early amyloid aggregation process are more toxic than mature fibrils, but pinpointing the exact toxic species among highly dynamic and heterogeneous aggregation intermediates remains a major challenge. β-barrel oligomers, structurally-determined recently for a slow-agg...

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Detalles Bibliográficos
Autores principales: Sun, Yunxiang, Ge, Xinwei, Xing, Yanting, Wang, Bo, Ding, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037789/
https://www.ncbi.nlm.nih.gov/pubmed/29985420
http://dx.doi.org/10.1038/s41598-018-28649-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037789/
https://www.ncbi.nlm.nih.gov/pubmed/29985420
http://dx.doi.org/10.1038/s41598-018-28649-7

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