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β-barrel Oligomers as Common Intermediates of Peptides Self-Assembling into Cross-β Aggregates
Oligomers populated during the early amyloid aggregation process are more toxic than mature fibrils, but pinpointing the exact toxic species among highly dynamic and heterogeneous aggregation intermediates remains a major challenge. β-barrel oligomers, structurally-determined recently for a slow-agg...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037789/ https://www.ncbi.nlm.nih.gov/pubmed/29985420 http://dx.doi.org/10.1038/s41598-018-28649-7 |