Cargando…

Human umbilical cord-derived mesenchymal stem cells direct macrophage polarization to alleviate pancreatic islets dysfunction in type 2 diabetic mice

Progressive pancreatic β-cell dysfunction is recognized as a fundamental pathology of type 2 diabetes (T2D). Recently, mesenchymal stem cells (MSCs) have been identified in protection of islets function in T2D individuals. However, the underlying mechanisms remain elusive. It is widely accepted that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yin, Yaqi, Hao, Haojie, Cheng, Yu, Zang, Li, Liu, Jiejie, Gao, Jieqing, Xue, Jing, Xie, Zongyan, Zhang, Qi, Han, Weidong, Mu, Yiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037817/ https://www.ncbi.nlm.nih.gov/pubmed/29988034 http://dx.doi.org/10.1038/s41419-018-0801-9

Ejemplares similares

Decitabine assists umbilical cord-derived mesenchymal stem cells in improving glucose homeostasis by modulating macrophage polarization in type 2 diabetic mice
por: Gao, Jieqing, et al.
Publicado: (2019)

Low-Dose Decitabine Assists Human Umbilical Cord-Derived Mesenchymal Stem Cells in Protecting β Cells via the Modulation of the Macrophage Phenotype in Type 2 Diabetic Mice
por: Xue, Jing, et al.
Publicado: (2020)

Mild hyperglycemia triggered islet function recovery in streptozotocin‐induced insulin‐deficient diabetic rats
por: Cheng, Yu, et al.
Publicado: (2016)

Human Umbilical Cord-Derived Mesenchymal Stem Cell Therapy Ameliorates Nonalcoholic Fatty Liver Disease in Obese Type 2 Diabetic Mice
por: Li, Bing, et al.
Publicado: (2019)

Human umbilical cord-derived mesenchymal stem cells ameliorate insulin resistance by suppressing NLRP3 inflammasome-mediated inflammation in type 2 diabetes rats
por: Sun, Xiaoya, et al.
Publicado: (2017)

Human umbilical cord-derived mesenchymal stem cells alleviate insulin resistance in diet-induced obese mice via an interaction with splenocytes
por: Xue, Jing, et al.
Publicado: (2022)

Anti-obesity effect and mechanism of mesenchymal stem cells influence on obese mice
por: Xie, Zongyan, et al.
Publicado: (2021)

Mesenchymal stem cell therapy in type 2 diabetes mellitus
por: Zang, Li, et al.
Publicado: (2017)

Umbilical Cord-derived Mesenchymal Stem Cells with Surfactant Protein B Alleviates Inflammatory Response in Acute Respiratory Distress Syndrome by Regulating Macrophage Polarization
por: Xu, Hongtao, et al.
Publicado: (2022)

Human umbilical cord blood-stem cells direct macrophage polarization and block inflammasome activation to alleviate rheumatoid arthritis
por: Shin, Tae-Hoon, et al.
Publicado: (2016)

A Conditioned Medium of Umbilical Cord Mesenchymal Stem Cells Overexpressing Wnt7a Promotes Wound Repair and Regeneration of Hair Follicles in Mice
por: Dong, Liang, et al.
Publicado: (2017)

Umbilical cord-derived mesenchymal stem cell extracts reduce colitis in mice by re-polarizing intestinal macrophages
por: Song, Ji-young, et al.
Publicado: (2017)

Exosomes derived from umbilical cord mesenchymal stem cells protect cartilage and regulate the polarization of macrophages in osteoarthritis
por: Li, Pengdong, et al.
Publicado: (2022)

Efficacy and safety of umbilical cord-derived mesenchymal stem cells in Chinese adults with type 2 diabetes: a single-center, double-blinded, randomized, placebo-controlled phase II trial
por: Zang, Li, et al.
Publicado: (2022)

LPS-preconditioned mesenchymal stromal cells modify macrophage polarization for resolution of chronic inflammation via exosome-shuttled let-7b
por: Ti, Dongdong, et al.
Publicado: (2015)

Human umbilical cord-derived mesenchymal stem cells alleviate oxidative stress-induced islet impairment via the Nrf2/HO-1 axis
por: Liu, Peng, et al.
Publicado: (2023)

Infusion of umbilical cord mesenchymal stem cells alleviates symptoms of ankylosing spondylitis
por: Li, Ai, et al.
Publicado: (2017)

The effects of IL-1β stimulated human umbilical cord mesenchymal stem cells on polarization and apoptosis of macrophages in rheumatoid arthritis
por: Zeng, Ying-Xuan, et al.
Publicado: (2023)

Exosomes from human umbilical cord mesenchymal stem cells attenuate the inflammation of severe steroid-resistant asthma by reshaping macrophage polarization
por: Dong, Bing, et al.
Publicado: (2021)

MicroRNA-146a-5p-modified human umbilical cord mesenchymal stem cells enhance protection against diabetic nephropathy in rats through facilitating M2 macrophage polarization
por: Zhang, Yaqi, et al.
Publicado: (2022)

Mesenchymal stem cells promote type 2 macrophage polarization to ameliorate the myocardial injury caused by diabetic cardiomyopathy
por: Jin, Liyuan, et al.
Publicado: (2019)

Umbilical Cord Mesenchymal Stem Cells Ameliorate Inflammation-Related Tumorigenesis via Modulating Macrophages
por: Fu, Yanxia, et al.
Publicado: (2022)

Infusion of Mesenchymal Stem Cells Ameliorates Hyperglycemia in Type 2 Diabetic Rats: Identification of a Novel Role in Improving Insulin Sensitivity
por: Si, Yiling, et al.
Publicado: (2012)

Human umbilical cord mesenchymal stem cell treatment alleviates symptoms in an atopic dermatitis-like mouse model
por: Hua, Chunting, et al.
Publicado: (2023)

Decorin Secreted by Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Induces Macrophage Polarization via CD44 to Repair Hyperoxic Lung Injury
por: Kwon, Ji Hye, et al.
Publicado: (2019)

Human Umbilical Cord Mesenchymal Stem Cells Improve the Necrosis and Osteocyte Apoptosis in Glucocorticoid-Induced Osteonecrosis of the Femoral Head Model through Reducing the Macrophage Polarization
por: Tian, Gang, et al.
Publicado: (2021)

Hypoxic culture of umbilical cord mesenchymal stem cell-derived sEVs prompts peripheral nerve injury repair
por: Zhu, Ziying, et al.
Publicado: (2023)

Human bone marrow-derived and umbilical cord-derived mesenchymal stem cells for alleviating neuropathic pain in a spinal cord injury model
por: Yousefifard, Mahmoud, et al.
Publicado: (2016)

Islet-Like Clusters Derived from Mesenchymal Stem Cells in Wharton's Jelly of the Human Umbilical Cord for Transplantation to Control Type 1 Diabetes
por: Chao, Kuo Ching, et al.
Publicado: (2008)

Human umbilical cord blood plasma alleviates age-related olfactory dysfunction by attenuating peripheral TNF-α expression
por: Lee, Byung-Chul, et al.
Publicado: (2019)

Soluble PTX3 of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Attenuates Hyperoxic Lung Injury by Activating Macrophage Polarization in Neonatal Rat Model
por: Kim, Miyeon, et al.
Publicado: (2020)

Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Regulate Macrophage Polarization to Attenuate Systemic Lupus Erythematosus-Associated Diffuse Alveolar Hemorrhage in Mice
por: Chen, Xun, et al.
Publicado: (2021)

Metformin Facilitates Osteoblastic Differentiation and M2 Macrophage Polarization by PI3K/AKT/mTOR Pathway in Human Umbilical Cord Mesenchymal Stem Cells
por: Shen, Min, et al.
Publicado: (2022)

Exosomes Derived From Umbilical Cord Mesenchymal Stem Cells Treat Cutaneous Nerve Damage and Promote Wound Healing
por: Zhu, Ziying, et al.
Publicado: (2022)

Human umbilical cord mesenchymal stem cells ameliorate acute liver failure by inhibiting apoptosis, inflammation and pyroptosis
por: Liu, Mengting, et al.
Publicado: (2021)

The Therapeutic Potential of Umbilical Cord Mesenchymal Stem Cells in Mice Premature Ovarian Failure
por: Wang, Shufang, et al.
Publicado: (2013)

Mechanism of mesenchymal stem cells in spinal cord injury repair through macrophage polarization
por: An, Nan, et al.
Publicado: (2021)

Extracellular Vesicles Derived from Three-Dimensional-Cultured Human Umbilical Cord Blood Mesenchymal Stem Cells Prevent Inflammation and Dedifferentiation in Pancreatic Islets
por: Lee, Eunwon, et al.
Publicado: (2023)

Human umbilical cord-derived mesenchymal stem cells alleviate schizophrenia-relevant behaviors in amphetamine-sensitized mice by inhibiting neuroinflammation
por: You, Min-Jung, et al.
Publicado: (2020)

Exosomes Derived from Umbilical Cord Mesenchymal Stem Cells Alleviate Mifepristone-Induced Human Endometrial Stromal Cell Injury
por: Wang, Jianye, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_a1oah6fvuricvpsqtgeif5sh35