Secondary pure red cell aplasia in multiple myeloma treated with lenalidomide

Pure red cell aplasia (PRCA) is a rare disorder characterized by marked erythroid hypoplasia with maturation arrest in the bone marrow. Secondary acquired PRCA may be associated with hematologic disorders. A few case reports have described PRCA associated with multiple myeloma (MM). However, the cli...

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Autores principales: Ito, Tomoki, Nakaya, Aya, Fujita, Shinya, Satake, Atsushi, Nakanishi, Takahisa, Azuma, Yoshiko, Tsubokura, Yukie, Konishi, Akiko, Hotta, Masaaki, Yoshimura, Hideaki, Ishii, Kazuyoshi, Nomura, Shosaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037886/
https://www.ncbi.nlm.nih.gov/pubmed/29998058
http://dx.doi.org/10.1016/j.lrr.2018.06.005
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author Ito, Tomoki
Nakaya, Aya
Fujita, Shinya
Satake, Atsushi
Nakanishi, Takahisa
Azuma, Yoshiko
Tsubokura, Yukie
Konishi, Akiko
Hotta, Masaaki
Yoshimura, Hideaki
Ishii, Kazuyoshi
Nomura, Shosaku
author_facet Ito, Tomoki
Nakaya, Aya
Fujita, Shinya
Satake, Atsushi
Nakanishi, Takahisa
Azuma, Yoshiko
Tsubokura, Yukie
Konishi, Akiko
Hotta, Masaaki
Yoshimura, Hideaki
Ishii, Kazuyoshi
Nomura, Shosaku
author_sort Ito, Tomoki
collection PubMed
description Pure red cell aplasia (PRCA) is a rare disorder characterized by marked erythroid hypoplasia with maturation arrest in the bone marrow. Secondary acquired PRCA may be associated with hematologic disorders. A few case reports have described PRCA associated with multiple myeloma (MM). However, the clinical course and mechanism of PRCA associated with MM remain unknown. We herein report two cases of PRCA associated with MM in patients undergoing treatment with lenalidomide.
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spelling pubmed-60378862018-07-11 Secondary pure red cell aplasia in multiple myeloma treated with lenalidomide Ito, Tomoki Nakaya, Aya Fujita, Shinya Satake, Atsushi Nakanishi, Takahisa Azuma, Yoshiko Tsubokura, Yukie Konishi, Akiko Hotta, Masaaki Yoshimura, Hideaki Ishii, Kazuyoshi Nomura, Shosaku Leuk Res Rep Article Pure red cell aplasia (PRCA) is a rare disorder characterized by marked erythroid hypoplasia with maturation arrest in the bone marrow. Secondary acquired PRCA may be associated with hematologic disorders. A few case reports have described PRCA associated with multiple myeloma (MM). However, the clinical course and mechanism of PRCA associated with MM remain unknown. We herein report two cases of PRCA associated with MM in patients undergoing treatment with lenalidomide. Elsevier 2018-07-07 /pmc/articles/PMC6037886/ /pubmed/29998058 http://dx.doi.org/10.1016/j.lrr.2018.06.005 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Ito, Tomoki
Nakaya, Aya
Fujita, Shinya
Satake, Atsushi
Nakanishi, Takahisa
Azuma, Yoshiko
Tsubokura, Yukie
Konishi, Akiko
Hotta, Masaaki
Yoshimura, Hideaki
Ishii, Kazuyoshi
Nomura, Shosaku
Secondary pure red cell aplasia in multiple myeloma treated with lenalidomide
title Secondary pure red cell aplasia in multiple myeloma treated with lenalidomide
title_full Secondary pure red cell aplasia in multiple myeloma treated with lenalidomide
title_fullStr Secondary pure red cell aplasia in multiple myeloma treated with lenalidomide
title_full_unstemmed Secondary pure red cell aplasia in multiple myeloma treated with lenalidomide
title_short Secondary pure red cell aplasia in multiple myeloma treated with lenalidomide
title_sort secondary pure red cell aplasia in multiple myeloma treated with lenalidomide
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037886/
https://www.ncbi.nlm.nih.gov/pubmed/29998058
http://dx.doi.org/10.1016/j.lrr.2018.06.005
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