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High Tidal Volume Induces Mitochondria Damage and Releases Mitochondrial DNA to Aggravate the Ventilator-Induced Lung Injury

OBJECTIVE: This study aimed to determine whether high tidal volume (HTV) induce mitochondria damage and mitophagy, contributing to the release of mitochondrial DNA (mtDNA). Another aim of the present study was to investigate the role and mechanism of mtDNA in ventilator-induced lung injury (VILI) in...

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Detalles Bibliográficos
Autores principales:	Lin, Jin-Yuan, Jing, Ren, Lin, Fei, Ge, Wan-yun, Dai, Hui-jun, Pan, Linghui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037891/ https://www.ncbi.nlm.nih.gov/pubmed/30018615 http://dx.doi.org/10.3389/fimmu.2018.01477

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