A Synthetic Cross-Species CD200R1 Agonist Suppresses Inflammatory Immune Responses In Vivo

Functional aptamers displaying agonistic or antagonistic properties are showing great promise as modulators of immune responses. Here, we report the development of a polyethylene glycol-modified (PEGylated) DNA aptamer as a cross-species (murine and human) CD200R1 agonist that modulates inflammatory...

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Detalles Bibliográficos
Autores principales: Prodeus, Aaron, Sparkes, Amanda, Fischer, Nicholas W., Cydzik, Marzena, Huang, Eric, Khatri, Ismat, Young, Ashley, Woo, Lindsay, Chow, Chung Wai, Gorczynski, Reginald, Gariépy, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037911/
https://www.ncbi.nlm.nih.gov/pubmed/30195773
http://dx.doi.org/10.1016/j.omtn.2018.05.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037911/
https://www.ncbi.nlm.nih.gov/pubmed/30195773
http://dx.doi.org/10.1016/j.omtn.2018.05.023

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