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ROS-mediated lysosomal membrane permeabilization is involved in bupivacaine-induced death of rabbit intervertebral disc cells

Bupivacaine is frequently administered for diagnosing and controlling spine-related pain in interventional spine procedures. However, the potential cytotoxic effects of bupivacaine on intervertebral disc (IVD) cells and the underlying molecular mechanisms have not yet been fully established. Here, w...

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Detalles Bibliográficos
Autores principales:	Cai, Xianyi, Liu, Yunlu, Hu, Yiqiang, Liu, Xianzhe, Jiang, Hongyan, Yang, Shuhua, Shao, Zengwu, Xia, Yun, Xiong, Liming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037912/ https://www.ncbi.nlm.nih.gov/pubmed/29986210 http://dx.doi.org/10.1016/j.redox.2018.06.010

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