Systemic DPP4 activity is reduced during primary HIV‐1 infection and is associated with intestinal RORC (+) CD4(+) cell levels: a surrogate marker candidate of HIV‐induced intestinal damage

INTRODUCTION: Combined anti‐retroviral therapy (cART) transformed HIV‐1 from a deadly disease into a chronic infection, but does not cure HIV infection. It also does not fully restore HIV‐induced gut damage unless administered extremely early after infection. Additional biomarkers are needed to eval...

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Detalles Bibliográficos
Autores principales: Ploquin, Mickaël J, Casrouge, Armanda, Madec, Yoann, Noël, Nicolas, Jacquelin, Beatrice, Huot, Nicolas, Duffy, Darragh, Jochems, Simon P, Micci, Luca, Lécuroux, Camille, Boufassa, Faroudy, Booiman, Thijs, Garcia‐Tellez, Thalia, Ghislain, Mathilde, Grand, Roger Le, Lambotte, Olivier, Kootstra, Neeltje, Meyer, Laurence, Goujard, Cecile, Paiardini, Mirko, Albert, Matthew L, Müller‐Trutwin, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038000/
https://www.ncbi.nlm.nih.gov/pubmed/29987877
http://dx.doi.org/10.1002/jia2.25144

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