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Human Umbilical Cord Blood Serum–derived α-Secretase: Functional Testing in Alzheimer’s Disease Mouse Models

Alzheimer’s disease (AD) is an age-related disorder that affects cognition. Our previous studies showed that the neuroprotective fragment of amyloid procurer protein (APP) metabolite, soluble APPα (sAPPα), interferes with β-site APP-cleaving enzyme 1 (BACE1, β-secretase) cleavage and reduces amyloid...

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Detalles Bibliográficos
Autores principales:	Habib, Ahsan, Hou, Huayan, Mori, Takashi, Tian, Jun, Zeng, Jin, Fan, Shengnuo, Giunta, Brian, Sanberg, Paul R., Sawmiller, Darrell, Tan, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038040/ https://www.ncbi.nlm.nih.gov/pubmed/29560732 http://dx.doi.org/10.1177/0963689718759473

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