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Multicomponent Reaction Based Synthesis of 1-Tetrazolylimidazo[1,5-a]pyridines

[Image: see text] A series of unprecedented tetrazole-linked imidazo[1,5-a]pyridines are synthesized from simple and readily available building blocks. The reaction sequence involves an azido-Ugi-deprotection reaction followed by an acetic anhydride-mediated N-acylation–cyclization process to afford...

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Detalles Bibliográficos
Autores principales: Kurhade, Santosh, Diekstra, Elmar, Sutanto, Fandi, Kurpiewska, Katarzyna, Kalinowska-Tłuścik, Justyna, Dömling, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038091/
https://www.ncbi.nlm.nih.gov/pubmed/29943994
http://dx.doi.org/10.1021/acs.orglett.8b01452