Synthetic α- and β-Ser-ADP-ribosylated Peptides Reveal α-Ser-ADPr as the Native Epimer

[Image: see text] A solid-phase methodology to synthesize oligopeptides, specifically incorporating serine residues linked to ADP-ribose (ADPr), is presented. Through the synthesis of both α- and β-anomers of the phosphoribosylated Fmoc-Ser building block and their usage in our modified solid-phase...

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Detalles Bibliográficos
Autores principales: Voorneveld, Jim, Rack, Johannes G. M., Ahel, Ivan, Overkleeft, Herman S., van der Marel, Gijsbert A., Filippov, Dmitri V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038095/
https://www.ncbi.nlm.nih.gov/pubmed/29947522
http://dx.doi.org/10.1021/acs.orglett.8b01742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038095/
https://www.ncbi.nlm.nih.gov/pubmed/29947522
http://dx.doi.org/10.1021/acs.orglett.8b01742

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