Cargando…
Synthetic α- and β-Ser-ADP-ribosylated Peptides Reveal α-Ser-ADPr as the Native Epimer
[Image: see text] A solid-phase methodology to synthesize oligopeptides, specifically incorporating serine residues linked to ADP-ribose (ADPr), is presented. Through the synthesis of both α- and β-anomers of the phosphoribosylated Fmoc-Ser building block and their usage in our modified solid-phase...
Autores principales: | Voorneveld, Jim, Rack, Johannes G. M., Ahel, Ivan, Overkleeft, Herman S., van der Marel, Gijsbert A., Filippov, Dmitri V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2018
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038095/ https://www.ncbi.nlm.nih.gov/pubmed/29947522 http://dx.doi.org/10.1021/acs.orglett.8b01742 |
Ejemplares similares
-
Molecular Tools for the Study of ADP‐Ribosylation: A Unified and Versatile Method to Synthesise Native Mono‐ADP‐Ribosylated Peptides
por: Voorneveld, Jim, et al.
Publicado: (2021) -
Mimetics of ADP-Ribosylated Histidine through Copper(I)-Catalyzed
Click Chemistry
por: Minnee, Hugo, et al.
Publicado: (2022) -
4-Thioribose
Analogues of Adenosine Diphosphate
Ribose (ADPr) Peptides
por: Madern, Jerre M., et al.
Publicado: (2023) -
Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal
por: Rack, Johannes Gregor Matthias, et al.
Publicado: (2021) -
Four of a Kind: A Complete
Collection of ADP-Ribosylated
Histidine Isosteres Using Cu(I)- and Ru(II)-Catalyzed Click Chemistry
por: Minnee, Hugo, et al.
Publicado: (2023)