Cargando…

The epithelial-mesenchymal transition induced by transcription factor LEF-1 is independent of β-catenin

Transcription factor lymphoid-enhancer–binding factor 1 (LEF-1) is a key molecule in the Wnt/β-catenin signaling pathway. Slug is one of the Wnt/β-catenin target genes and can induce epithelial–mesenchymal transition (EMT). Previously, we have shown that not only wild-type LEF-1 but also LEF-1 lacki...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kobayashi, Wakako, Ozawa, Masayuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038150/ https://www.ncbi.nlm.nih.gov/pubmed/29998192 http://dx.doi.org/10.1016/j.bbrep.2018.06.003

Ejemplares similares

The ectopic expression of Snail in MDBK cells does not induce epithelial-mesenchymal transition
por: IZAWA, GENYA, et al.
Publicado: (2015)

β-Catenin/LEF-1 transcription complex is responsible for the transcriptional activation of LINC01278
por: Lin, Shaojian, et al.
Publicado: (2021)

Past Visits Present: TCF/LEFs Partner with ATFs for β-Catenin–Independent Activity
por: Sprowl, Stephanie, et al.
Publicado: (2013)

VBP1 modulates Wnt/β-catenin signaling by mediating the stability of the transcription factors TCF/LEFs
por: Zhang, Haifeng, et al.
Publicado: (2021)

β-Catenin-Independent Activation of TCF1/LEF1 in Human Hematopoietic Tumor Cells through Interaction with ATF2 Transcription Factors
por: Grumolato, Luca, et al.
Publicado: (2013)

β-catenin activates TGF-β-induced epithelial–mesenchymal transition in adenomyosis
por: Yoo, Jung-Yoon, et al.
Publicado: (2020)

TGFβ(3) signaling activates transcription of the LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development
por: Nawshad, Ali, et al.
Publicado: (2003)

293 cells express both epithelial as well as mesenchymal cell adhesion molecules
por: INADA, MASAKAZU, et al.
Publicado: (2016)

Epac1 links prostaglandin E(2) to β-catenin-dependent transcription during epithelial-to-mesenchymal transition
por: Jansen, Sepp R., et al.
Publicado: (2016)

β-Catenin/Smad3 Interaction Regulates Transforming Growth Factor-β-Induced Epithelial to Mesenchymal Transition in the Lens
por: Taiyab, Aftab, et al.
Publicado: (2019)

Transcriptional factors associated with epithelial-mesenchymal transition in choroidal neovascularization
por: Hirasawa, Manabu, et al.
Publicado: (2011)

β-Catenin/CBP–Dependent Signaling Regulates TGF-β–Induced Epithelial to Mesenchymal Transition of Lens Epithelial Cells
por: Taiyab, Aftab, et al.
Publicado: (2016)

LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells
por: Morgan, Rhys G., et al.
Publicado: (2019)

Epithelial Mesenchymal Transition by C-Fos Estrogen Receptor Activation Involves Nuclear Translocation of β-Catenin and Upregulation of β-Catenin/Lymphoid Enhancer Binding Factor-1 Transcriptional Activity
por: Eger, Andreas, et al.
Publicado: (2000)

Fascin Induces Epithelial-Mesenchymal Transition of Cholangiocarcinoma Cells by Regulating Wnt/β-Catenin Signaling
por: Mao, Xianhai, et al.
Publicado: (2016)

β-catenin/LEF1/IGF-IIR Signaling Axis Galvanizes the Angiotensin-II- induced Cardiac Hypertrophy
por: Lai, Chin-Hu, et al.
Publicado: (2019)

Sirtuin 7 Promotes Mesenchymal to Epithelial Transition by β-Catenin Redistribution and Stabilization
por: Kiran, Shashi, et al.
Publicado: (2020)

β-Catenin and TCFs/LEF signaling discordantly regulate IL-6 expression in astrocytes
por: Robinson, KaReisha F., et al.
Publicado: (2020)

Pja2 Inhibits Wnt/β-catenin Signaling by Reducing the Level of TCF/LEF1
por: Song, Yonghee, et al.
Publicado: (2018)

GOLPH3 induces epithelial–mesenchymal transition via Wnt/β‐catenin signaling pathway in epithelial ovarian cancer
por: Sun, Jing, et al.
Publicado: (2017)

Linc-ROR induces epithelial-to-mesenchymal transition in ovarian cancer by increasing Wnt/β-catenin signaling
por: Lou, Yanhui, et al.
Publicado: (2017)

Monoubiquitination of p120-catenin is essential for TGFβ-induced epithelial-mesenchymal transition and tumor metastasis
por: Wu, Qingang, et al.
Publicado: (2020)

Oct4 induces EMT through LEF1/β-catenin dependent WNT signaling pathway in hepatocellular carcinoma
por: Sun, Lu, et al.
Publicado: (2017)

Epithelial–mesenchymal transition and its transcription factors
por: Debnath, Pallabi, et al.
Publicado: (2021)

The critical role of EGF-β-catenin signaling in the epithelial-mesenchymal transition in human glioblastoma
por: Wang, Xingqiang, et al.
Publicado: (2017)

LEF1 enhances β-catenin transactivation through IDR-dependent liquid–liquid phase separation
por: Zhao, Bing, et al.
Publicado: (2023)

A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells
por: Guo, Qiuyu, et al.
Publicado: (2021)

PARsylated transcription factor EB (TFEB) regulates the expression of a subset of Wnt target genes by forming a complex with β-catenin-TCF/LEF1
por: Kim, Soyoung, et al.
Publicado: (2021)

Survivin expression promotes VEGF-induced tumor angiogenesis via PI3K/Akt enhanced β-catenin/Tcf-Lef dependent transcription
por: Fernández, Jaime G, et al.
Publicado: (2014)

PCDHGA9 represses epithelial-mesenchymal transition and metastatic potential in gastric cancer cells by reducing β-catenin transcriptional activity
por: Weng, Junyong, et al.
Publicado: (2020)

LncRNA LEF1-AS1 promotes metastasis of prostatic carcinoma via the Wnt/β-catenin pathway
por: Li, Weiyuan, et al.
Publicado: (2020)

FERMT3 mediates cigarette smoke-induced epithelial–mesenchymal transition through Wnt/β-catenin signaling
por: Su, Xiaoshan, et al.
Publicado: (2021)

1α, 25-dihydroxyvitamin D(3) inhibits transforming growth factor β1-induced epithelial-mesenchymal transition via β-catenin pathway
por: Xiong, Xin-Rong, et al.
Publicado: (2020)

Correction: A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells
por: Guo, Qiuyu, et al.
Publicado: (2021)

A novel cell-penetrating peptide suppresses breast tumorigenesis by inhibiting β-catenin/LEF-1 signaling
por: Hsieh, Tsung-Hua, et al.
Publicado: (2016)

A Positive Role of Cadherin in Wnt/β-Catenin Signalling during Epithelial-Mesenchymal Transition
por: Howard, Sara, et al.
Publicado: (2011)

Cyclin G2 inhibits epithelial-to-mesenchymal transition by disrupting Wnt/β-catenin signaling
por: Bernaudo, S, et al.
Publicado: (2016)

FHL2 promotes tubular epithelial‐to‐mesenchymal transition through modulating β‐catenin signalling
por: Cai, Ting, et al.
Publicado: (2017)

Janus kinase 3 regulates adherens junctions and epithelial mesenchymal transition through β-catenin
por: Mishra, Jayshree, et al.
Publicado: (2017)

FOXC1 silencing inhibits the epithelial-to-mesenchymal transition of glioma cells: Involvement of β-catenin signaling
por: Cao, Qinchen, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_0n815il7qqsdtei76ssutr5n6b