Inhibition of endoplasmic-reticulum-stress-mediated autophagy enhances the effectiveness of chemotherapeutics on pancreatic cancer

BACKGROUND: Endoplasmic reticulum (ER) stress and its consequent unfolded protein response (UPR) are believed to be associated with progression, survival and chemoresistance of a variety of tumor cells through multiple cellular processes, including autophagy. Therefore, the ER stress-autophagy pathw...

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Detalles Bibliográficos
Autores principales: Thakur, Prakash C., Miller-Ocuin, Jennifer L., Nguyen, Khanh, Matsuda, Rina, Singhi, Aatur D., Zeh, Herbert J., Bahary, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038181/
https://www.ncbi.nlm.nih.gov/pubmed/29986726
http://dx.doi.org/10.1186/s12967-018-1562-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038181/
https://www.ncbi.nlm.nih.gov/pubmed/29986726
http://dx.doi.org/10.1186/s12967-018-1562-z

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