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Inflammation-induced DNA methylation of DNA polymerase gamma alters the metabolic profile of colon tumors

BACKGROUND: Inflammation, metabolism, and epigenetic modulation are highly interconnected processes that can be altered during tumorigenesis. However, because of the complexity of these interactions, direct cause and effect during tumorigenesis have been difficult to prove. Previously, using a murin...

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Detalles Bibliográficos
Autores principales: Maiuri, Ashley R., Li, Hongde, Stein, Barry D., Tennessen, Jason M., O’Hagan, Heather M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038244/
https://www.ncbi.nlm.nih.gov/pubmed/30002826
http://dx.doi.org/10.1186/s40170-018-0182-7