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Protein phosphatase 2A activation mechanism contributes to JS-K induced caspase-dependent apoptosis in human hepatocellular carcinoma cells

BACKGROUND: JS-K is a nitric oxide (NO) donor and could generate intracellularly high levels of NO. The study explores PP2A as a tumor suppressor is a major determinant mediating JS-K-caused apoptosis in human hepatocellular carcinoma (HCC) cells. METHODS: The human HCC cell lines (PLC5, Huh-7, Bel-...

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Detalles Bibliográficos
Autores principales:	Liu, Ling, Huang, Zile, Chen, Jingjing, Wang, Jiangang, Wang, Shuying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038275/ https://www.ncbi.nlm.nih.gov/pubmed/29986744 http://dx.doi.org/10.1186/s13046-018-0823-2

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