Cargando…

Novel long-range regulatory mechanisms controlling PKD2 gene expression

BACKGROUND: Cis-regulatory elements control gene expression over large distances through the formation of chromatin loops, which allow contact between enhancers and gene promoters. Alterations in cis-acting regulatory systems could be linked to human genetic diseases. Here, we analyse the spatial or...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moisan, Stéphanie, Levon, Stéphanie, Cornec-Le Gall, Emilie, Le Meur, Yannick, Audrézet, Marie-Pierre, Dostie, Josée, Férec, Claude
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038307/ https://www.ncbi.nlm.nih.gov/pubmed/29986647 http://dx.doi.org/10.1186/s12864-018-4892-6

Ejemplares similares

Analysis of long-range interactions in primary human cells identifies cooperative CFTR regulatory elements
por: Moisan, Stéphanie, et al.
Publicado: (2016)

CFTR Cooperative Cis-Regulatory Elements in Intestinal Cells
por: Collobert, Mégane, et al.
Publicado: (2021)

3D Chromatin Organization Involving MEIS1 Factor in the cis-Regulatory Landscape of GJB2
por: Le Nabec, Anaïs, et al.
Publicado: (2022)

Tissue-Specific Regulation of CFTR Gene Expression
por: Blotas, Clara, et al.
Publicado: (2023)

A Conservative Assessment of the Major Genetic Causes of Idiopathic Chronic Pancreatitis: Data from a Comprehensive Analysis of PRSS1, SPINK1, CTRC and CFTR Genes in 253 Young French Patients
por: Masson, Emmanuelle, et al.
Publicado: (2013)

Whole-Genome Sequencing Improves the Diagnosis of DFNB1 Monoallelic Patients
por: Le Nabec, Anaïs, et al.
Publicado: (2021)

Evidence for decline in the incidence of cystic fibrosis: a 35-year observational study in Brittany, France
por: Scotet, Virginie, et al.
Publicado: (2012)

The Talented LncRNAs: Meshing into Transcriptional Regulatory Networks in Cancer
por: Segal, Dana, et al.
Publicado: (2023)

Flank pain has a significant adverse impact on quality of life in ADPKD: the CYSTic-QoL study
por: Winterbottom, Jean, et al.
Publicado: (2022)

Design, Synthesis, and Biological Evaluation of PKD Inhibitors
por: George, Kara M., et al.
Publicado: (2011)

Pkd1 and Pkd2 Are Required for Normal Placental Development
por: Garcia-Gonzalez, Miguel A., et al.
Publicado: (2010)

A conserved HOTAIRM1-HOXA1 regulatory axis contributes early to neuronal differentiation
por: Segal, Dana, et al.
Publicado: (2023)

Role of PKD2 in Rheotaxis in Dictyostelium
por: Lima, Wanessa C., et al.
Publicado: (2014)

High Resolution Melt analysis for mutation screening in PKD1 and PKD2
por: Bataille, Stanislas, et al.
Publicado: (2011)

Booming far: the long-range vocal strategy of a lekking bird
por: Cornec, C., et al.
Publicado: (2017)

Can we further enrich autosomal dominant polycystic kidney disease clinical trials for rapidly progressive patients? Application of the PROPKD score in the TEMPO trial
por: Cornec-Le Gall, Emilie, et al.
Publicado: (2018)

p53 mutation regulates PKD genes and results in co-occurrence of PKD and tumorigenesis
por: Li, Haili, et al.
Publicado: (2019)

PKD1 and PKD2 mutations in Slovenian families with autosomal dominant polycystic kidney disease
por: Vouk, Katja, et al.
Publicado: (2006)

Polycystic Kidney Disease Caused by Bilineal Inheritance of Truncating PKD1 as Well as PKD2 Mutations
por: Losekoot, Monique, et al.
Publicado: (2020)

PKD1 and PKD2 mRNA cis-inhibition drives polycystic kidney disease progression
por: Lakhia, Ronak, et al.
Publicado: (2022)

Small Interactor of PKD2 (SIP), a novel PKD2-related single-pass transmembrane protein, is required for proteolytic processing and ciliary import of Chlamydomonas PKD2
por: Das, Poulomi, et al.
Publicado: (2023)

Chromatin Insulator Factors Involved in Long-Range DNA Interactions and Their Role in the Folding of the Drosophila Genome
por: Vogelmann, Jutta, et al.
Publicado: (2014)

Mesangial Cell-Specific Antibodies Are Central to the Pathogenesis of Lupus Nephritis
por: Seret, Guillaume, et al.
Publicado: (2012)

Using Bacterial Artificial Chromosomes in Leukemia Research: The Experience at the University Cytogenetics Laboratory in Brest, France
por: De Braekeleer, Etienne, et al.
Publicado: (2011)

Identification of novel PKD1 and PKD2 mutations in Korean patients with autosomal dominant polycystic kidney disease
por: Choi, Rihwa, et al.
Publicado: (2014)

PKD1 Compared With PKD2 Genotype and Cardiac Hospitalizations in the Halt Progression of Polycystic Kidney Disease Studies
por: Steele, Cortney, et al.
Publicado: (2021)

Identified eleven exon variants in PKD1 and PKD2 genes that altered RNA splicing by minigene assay
por: Liu, Xuyan, et al.
Publicado: (2023)

Non-Native Interactions Are Critical for Mechanical Strength in PKD Domains
por: Forman, Julia R., et al.
Publicado: (2009)

Vitamin K antagonist has a higher impact than heparin in preventing circuit clotting in chronic haemodialysis patients
por: Charles, Pierre-Yves, et al.
Publicado: (2019)

Identification of novel PKD1 and PKD2 mutations in a Chinese population with autosomal dominant polycystic kidney disease
por: Liu, Bei, et al.
Publicado: (2015)

Prediction of Renal Prognosis in Patients with Autosomal Dominant Polycystic Kidney Disease Using PKD1/PKD2 Mutations
por: Kataoka, Hiroshi, et al.
Publicado: (2020)

Structural basis for Ca(2+) activation of the heteromeric PKD1L3/PKD2L1 channel
por: Su, Qiang, et al.
Publicado: (2021)

Correction: Role of PKD2 in Rheotaxis in Dictyostelium
Publicado: (2014)

Mapping the Shh long-range regulatory domain
por: Anderson, Eve, et al.
Publicado: (2014)

Diagnosis of autosomal dominant polycystic kidney disease using efficient PKD1 and PKD2 targeted next-generation sequencing
por: Trujillano, Daniel, et al.
Publicado: (2014)

The response of PKD1L3 / PKD2L1 to acid stimuli is inhibited by capsaicin and its pungent analogs
por: Ishii, Sho, et al.
Publicado: (2012)

Corrigendum: Identification of novel PKD1 and PKD2 mutations in a Chinese population with autosomal dominant polycystic kidney disease
por: Liu, Bei, et al.
Publicado: (2016)

Deciphering Variability of PKD1 and PKD2 in an Italian Cohort of 643 Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD)
por: Carrera, Paola, et al.
Publicado: (2016)

Hypomorphic PKD1 Alleles Impact Disease Variability in Autosomal Dominant Polycystic Kidney Disease
por: Gulati, Ashima, et al.
Publicado: (2023)

Nuclear Eukaryotic Initiation Factor 4e (Eif4e) Colocalizes with Splicing Factors in Speckles
por: Dostie, Josée, et al.
Publicado: (2000)

Cannot write session to /tmp/vufind_sessions/sess_4d99uunku3s6hse97ahr95jakp