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Obesity Exacerbates the Cytokine Storm Elicited by Francisella tularensis Infection of Females and Is Associated with Increased Mortality
Infection with Francisella tularensis, the causative agent of the human disease tularemia, results in the overproduction of inflammatory cytokines, termed the cytokine storm. Excess metabolic byproducts of obesity accumulate in obese individuals and activate the same inflammatory signaling pathways...
Autores principales: | Ramos Muniz, Mireya G., Palfreeman, Matthew, Setzu, Nicole, Sanchez, Michelle A., Saenz Portillo, Pamela, Garza, Kristine M., Gosselink, Kristin L., Spencer, Charles T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038682/ https://www.ncbi.nlm.nih.gov/pubmed/30046592 http://dx.doi.org/10.1155/2018/3412732 |
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