Microevolution and Patterns of Transmission of Shigella sonnei within Cyclic Outbreaks Shigellosis, Israel

Whole-genome sequencing unveiled host and environment-related insights to Shigella sonnei transmission within cyclic epidemics during 2000–2012 in Israel. The Israeli reservoir contains isolates belonging to S. sonnei lineage III but of different origin, shows loss of tetracycline resistance genes,...

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Autores principales: Behar, Adi, Baker, Kate Susan, Bassal, Ravit, Ezernitchi, Analia, Valinsky, Lea, Thomson, Nicholas R., Cohen, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2018
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038740/
https://www.ncbi.nlm.nih.gov/pubmed/29912703
http://dx.doi.org/10.3201/eid2407.171313
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author Behar, Adi
Baker, Kate Susan
Bassal, Ravit
Ezernitchi, Analia
Valinsky, Lea
Thomson, Nicholas R.
Cohen, Daniel
author_facet Behar, Adi
Baker, Kate Susan
Bassal, Ravit
Ezernitchi, Analia
Valinsky, Lea
Thomson, Nicholas R.
Cohen, Daniel
author_sort Behar, Adi
collection PubMed
description Whole-genome sequencing unveiled host and environment-related insights to Shigella sonnei transmission within cyclic epidemics during 2000–2012 in Israel. The Israeli reservoir contains isolates belonging to S. sonnei lineage III but of different origin, shows loss of tetracycline resistance genes, and little genetic variation within the O antigen: highly relevant for Shigella vaccine development.
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spelling pubmed-60387402018-07-11 Microevolution and Patterns of Transmission of Shigella sonnei within Cyclic Outbreaks Shigellosis, Israel Behar, Adi Baker, Kate Susan Bassal, Ravit Ezernitchi, Analia Valinsky, Lea Thomson, Nicholas R. Cohen, Daniel Emerg Infect Dis Dispatch Whole-genome sequencing unveiled host and environment-related insights to Shigella sonnei transmission within cyclic epidemics during 2000–2012 in Israel. The Israeli reservoir contains isolates belonging to S. sonnei lineage III but of different origin, shows loss of tetracycline resistance genes, and little genetic variation within the O antigen: highly relevant for Shigella vaccine development. Centers for Disease Control and Prevention 2018-07 /pmc/articles/PMC6038740/ /pubmed/29912703 http://dx.doi.org/10.3201/eid2407.171313 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Behar, Adi
Baker, Kate Susan
Bassal, Ravit
Ezernitchi, Analia
Valinsky, Lea
Thomson, Nicholas R.
Cohen, Daniel
Microevolution and Patterns of Transmission of Shigella sonnei within Cyclic Outbreaks Shigellosis, Israel
title Microevolution and Patterns of Transmission of Shigella sonnei within Cyclic Outbreaks Shigellosis, Israel
title_full Microevolution and Patterns of Transmission of Shigella sonnei within Cyclic Outbreaks Shigellosis, Israel
title_fullStr Microevolution and Patterns of Transmission of Shigella sonnei within Cyclic Outbreaks Shigellosis, Israel
title_full_unstemmed Microevolution and Patterns of Transmission of Shigella sonnei within Cyclic Outbreaks Shigellosis, Israel
title_short Microevolution and Patterns of Transmission of Shigella sonnei within Cyclic Outbreaks Shigellosis, Israel
title_sort microevolution and patterns of transmission of shigella sonnei within cyclic outbreaks shigellosis, israel
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038740/
https://www.ncbi.nlm.nih.gov/pubmed/29912703
http://dx.doi.org/10.3201/eid2407.171313
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