Avian Influenza A Virus Infection among Workers at Live Poultry Markets, China, 2013–2016

We conducted a 3-year longitudinal serologic survey on an open cohort of poultry workers, swine workers, and general population controls to assess avian influenza A virus (AIV) seroprevalence and seroincidence and virologic diversity at live poultry markets (LPMs) in Wuxi City, Jiangsu Province, Chi...

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Detalles Bibliográficos
Autores principales: Ma, Mai-Juan, Zhao, Teng, Chen, Shan-Hui, Xia, Xian, Yang, Xiao-Xian, Wang, Guo-Lin, Fang, Li-Qun, Ma, Guan-Yuan, Wu, Meng-Na, Qian, Yan-Hua, Dean, Natalie E., Yang, Yang, Lu, Bing, Cao, Wu-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038753/
https://www.ncbi.nlm.nih.gov/pubmed/29912708
http://dx.doi.org/10.3201/eid2407.172059
Descripción
Sumario:We conducted a 3-year longitudinal serologic survey on an open cohort of poultry workers, swine workers, and general population controls to assess avian influenza A virus (AIV) seroprevalence and seroincidence and virologic diversity at live poultry markets (LPMs) in Wuxi City, Jiangsu Province, China. Of 964 poultry workers, 9 (0.93%) were seropositive for subtype H7N9 virus, 18 (1.87%) for H9N2, and 18 (1.87%) for H5N1. Of 468 poultry workers followed longitudinally, 2 (0.43%), 13 (2.78%), and 7 (1.5%) seroconverted, respectively; incidence was 1.27, 8.28, and 4.46/1,000 person-years for H7N9, H9N2, and H5N1 viruses, respectively. Longitudinal surveillance of AIVs at 9 LPMs revealed high co-circulation of H9, H7, and H5 subtypes. We detected AIVs in 726 (23.3%) of 3,121 samples and identified a high diversity (10 subtypes) of new genetic constellations and reassortant viruses. These data suggest that stronger surveillance for AIVs within LPMs and high-risk populations is imperative.

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