Unfolding of a ClC chloride transporter retains memory of its evolutionary history

ClC chloride channels and transporters are important for chloride homeostasis in species from bacteria to human. Mutations in ClC proteins cause genetically inherited diseases, some of which are likely to have folding defects. The ClC proteins present a challenging and unusual biological folding pro...

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Detalles Bibliográficos
Autores principales: Min, Duyoung, Jefferson, Robert E., Qi, Yifei, Wang, Jing Yang, Arbing, Mark A., Im, Wonpil, Bowie, James U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038805/
https://www.ncbi.nlm.nih.gov/pubmed/29581582
http://dx.doi.org/10.1038/s41589-018-0025-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038805/
https://www.ncbi.nlm.nih.gov/pubmed/29581582
http://dx.doi.org/10.1038/s41589-018-0025-4

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