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Unfolding of a ClC chloride transporter retains memory of its evolutionary history
ClC chloride channels and transporters are important for chloride homeostasis in species from bacteria to human. Mutations in ClC proteins cause genetically inherited diseases, some of which are likely to have folding defects. The ClC proteins present a challenging and unusual biological folding pro...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038805/ https://www.ncbi.nlm.nih.gov/pubmed/29581582 http://dx.doi.org/10.1038/s41589-018-0025-4 |