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Structural characterization of free-state and product-state Mycobacterium tuberculosis methionyl-tRNA synthetase reveals an induced-fit ligand-recognition mechanism

Mycobacterium tuberculosis (MTB) caused 10.4 million cases of tuberculosis and 1.7 million deaths in 2016. The incidence of multidrug-resistant and extensively drug-resistant MTB is becoming an increasing threat to public health and the development of novel anti-MTB drugs is urgently needed. Methion...

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Detalles Bibliográficos
Autores principales:	Wang, Wei, Qin, Bo, Wojdyla, Justyna Aleksandra, Wang, Meitian, Gao, Xiaopan, Cui, Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2018
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038951/ https://www.ncbi.nlm.nih.gov/pubmed/30002848 http://dx.doi.org/10.1107/S2052252518008217

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