Cell fate decisions of human iPSC-derived bipotential hepatoblasts depend on cell density

During embryonic development bipotential hepatoblasts differentiate into hepatocytes and cholangiocytes- the two main cell types within the liver. Cell fate decision depends on elaborate interactions between distinct signalling pathways, namely Notch, WNT, TGFβ, and Hedgehog. Several in vitro protoc...

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Detalles Bibliográficos
Autores principales: Graffmann, Nina, Ncube, Audrey, Wruck, Wasco, Adjaye, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039024/
https://www.ncbi.nlm.nih.gov/pubmed/29990377
http://dx.doi.org/10.1371/journal.pone.0200416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039024/
https://www.ncbi.nlm.nih.gov/pubmed/29990377
http://dx.doi.org/10.1371/journal.pone.0200416

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