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The two shapes of the Tau protein
Tau proteins can convert from an inert shape to a misfolded shape that seeds the growth of fibers that contribute to the pathology of Alzheimer’s disease.
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039172/ https://www.ncbi.nlm.nih.gov/pubmed/29988017 http://dx.doi.org/10.7554/eLife.38516 |
| _version_ | 1783338633684582400 |
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| author | Kelly, Jeffery W |
| author_facet | Kelly, Jeffery W |
| author_sort | Kelly, Jeffery W |
| collection | PubMed |
| description | Tau proteins can convert from an inert shape to a misfolded shape that seeds the growth of fibers that contribute to the pathology of Alzheimer’s disease. |
| format | Online Article Text |
| id | pubmed-6039172 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2018 |
| publisher | eLife Sciences Publications, Ltd |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-60391722018-07-11 The two shapes of the Tau protein Kelly, Jeffery W eLife Biochemistry and Chemical Biology Tau proteins can convert from an inert shape to a misfolded shape that seeds the growth of fibers that contribute to the pathology of Alzheimer’s disease. eLife Sciences Publications, Ltd 2018-07-10 /pmc/articles/PMC6039172/ /pubmed/29988017 http://dx.doi.org/10.7554/eLife.38516 Text en © 2018, Kelly http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited. |
| spellingShingle | Biochemistry and Chemical Biology Kelly, Jeffery W The two shapes of the Tau protein |
| title | The two shapes of the Tau protein |
| title_full | The two shapes of the Tau protein |
| title_fullStr | The two shapes of the Tau protein |
| title_full_unstemmed | The two shapes of the Tau protein |
| title_short | The two shapes of the Tau protein |
| title_sort | two shapes of the tau protein |
| topic | Biochemistry and Chemical Biology |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039172/ https://www.ncbi.nlm.nih.gov/pubmed/29988017 http://dx.doi.org/10.7554/eLife.38516 |
| work_keys_str_mv | AT kellyjefferyw thetwoshapesofthetauprotein AT kellyjefferyw twoshapesofthetauprotein |