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The anti-fecundity effect of 5-azacytidine (5-AzaC) on Schistosoma mansoni is linked to dis-regulated transcription, translation and stem cell activities

Uncontrolled host immunological reactions directed against tissue-trapped eggs precipitate a potentially lethal, pathological cascade responsible for schistosomiasis. Blocking schistosome egg production, therefore, presents a strategy for simultaneously reducing immunopathology as well as limiting d...

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Detalles Bibliográficos
Autores principales: Geyer, Kathrin K., Munshi, Sabrina E., Vickers, Martin, Squance, Michael, Wilkinson, Toby J., Berrar, Daniel, Chaparro, Cristian, Swain, Martin T., Hoffmann, Karl F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039303/
https://www.ncbi.nlm.nih.gov/pubmed/29649665
http://dx.doi.org/10.1016/j.ijpddr.2018.03.006

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