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The transcription factor SKN-1 and detoxification gene ugt-22 alter albendazole efficacy in Caenorhabditis elegans

Parasitic nematodes infect over 1/4 th of the human population and are a major burden on livestock and crop production. Benzimidazole class anthelmintics are widely used to treat infections, but resistance is a widespread problem. Mutation of genes encoding the benzimidazole target β-tubulin is a we...

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Detalles Bibliográficos
Autores principales: Fontaine, Pauline, Choe, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039320/
https://www.ncbi.nlm.nih.gov/pubmed/29793058
http://dx.doi.org/10.1016/j.ijpddr.2018.04.006

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