Site-specific ion occupation in the selectivity filter causes voltage-dependent gating in a viral K(+) channel

Many potassium channels show voltage-dependent gating without a dedicated voltage sensor domain. This is not fully understood yet, but often explained by voltage-induced changes of ion occupation in the five distinct K(+) binding sites in the selectivity filter. To better understand this mechanism o...

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Detalles Bibliográficos
Autores principales: Rauh, O., Hansen, U. P., Scheub, D. D., Thiel, G., Schroeder, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039446/
https://www.ncbi.nlm.nih.gov/pubmed/29991721
http://dx.doi.org/10.1038/s41598-018-28751-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039446/
https://www.ncbi.nlm.nih.gov/pubmed/29991721
http://dx.doi.org/10.1038/s41598-018-28751-w

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