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An allelic variant in the intergenic region between ERAP1 and ERAP2 correlates with an inverse expression of the two genes
The Endoplasmatic Reticulum Aminopeptidases ERAP1 and ERAP2 are implicated in a variety of immune and non-immune functions. Most studies however have focused on their role in shaping the HLA class I peptidome by trimming peptides to the optimal size. Genome Wide Association Studies highlighted non-s...
Autores principales: | Paladini, Fabiana, Fiorillo, Maria Teresa, Vitulano, Carolina, Tedeschi, Valentina, Piga, Matteo, Cauli, Alberto, Mathieu, Alessandro, Sorrentino, Rosa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039459/ https://www.ncbi.nlm.nih.gov/pubmed/29991817 http://dx.doi.org/10.1038/s41598-018-28799-8 |
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