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Integrative genomic analysis of adult mixed phenotype acute leukemia delineates lineage associated molecular subtypes

Mixed phenotype acute leukemia (MPAL) is a rare subtype of acute leukemia characterized by leukemic blasts presenting myeloid and lymphoid markers. Here we report data from integrated genomic analysis on 31 MPAL samples and compare molecular profiling with that from acute myeloid leukemia (AML), B c...

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Detalles Bibliográficos
Autores principales: Takahashi, Koichi, Wang, Feng, Morita, Kiyomi, Yan, Yuanqing, Hu, Peter, Zhao, Pei, Zhar, Abdallah Abou, Wu, Chang Jiun, Gumbs, Curtis, Little, Latasha, Tippen, Samantha, Thornton, Rebecca, Coyle, Marcus, Mendoza, Marisela, Thompson, Erika, Zhang, Jianhua, DiNardo, Courtney D., Jain, Nitin, Ravandi, Farhad, Cortes, Jorge E., Garcia-Manero, Guillermo, Kornblau, Steven, Andreeff, Michael, Jabbour, Elias, Bueso-Ramos, Carlos, Takaori-Kondo, Akifumi, Konopleva, Marina, Patel, Keyur, Kantarjian, Hagop, Futreal, P. Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039465/
https://www.ncbi.nlm.nih.gov/pubmed/29991687
http://dx.doi.org/10.1038/s41467-018-04924-z