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The Co-operation of RUNX1 with LDB1, CDK9 and BRD4 Drives Transcription Factor Complex Relocation During Haematopoietic Specification
Haematopoietic cells arise from endothelial cells within the dorsal aorta of the embryo via a process called the endothelial-haematopoietic transition (EHT). This process crucially depends on the transcription factor RUNX1 which rapidly activates the expression of genes essential for haematopoietic...
Autores principales: | Gilmour, Jane, Assi, Salam A., Noailles, Laura, Lichtinger, Monika, Obier, Nadine, Bonifer, Constanze |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039467/ https://www.ncbi.nlm.nih.gov/pubmed/29991720 http://dx.doi.org/10.1038/s41598-018-28506-7 |
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