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Central insulin action induces activation of paraventricular oxytocin neurons to release oxytocin into circulation

Oxytocin neurons in the paraventricular nucleus (PVN) of hypothalamus regulate energy metabolism and reproduction. Plasma oxytocin concentration is reduced in obese subjects with insulin resistance. These findings prompted us to hypothesize that insulin serves to promote oxytocin release. This study...

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Detalles Bibliográficos
Autores principales: Zhang, Boyang, Nakata, Masanori, Nakae, Jun, Ogawa, Wataru, Yada, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039480/
https://www.ncbi.nlm.nih.gov/pubmed/29991705
http://dx.doi.org/10.1038/s41598-018-28816-w

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