Detection and removal of barcode swapping in single-cell RNA-seq data

Barcode swapping results in the mislabelling of sequencing reads between multiplexed samples on patterned flow-cell Illumina sequencing machines. This may compromise the validity of numerous genomic assays; however, the severity and consequences of barcode swapping remain poorly understood. We have...

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Detalles Bibliográficos
Autores principales: Griffiths, Jonathan A., Richard, Arianne C., Bach, Karsten, Lun, Aaron T. L., Marioni, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039488/
https://www.ncbi.nlm.nih.gov/pubmed/29991676
http://dx.doi.org/10.1038/s41467-018-05083-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039488/
https://www.ncbi.nlm.nih.gov/pubmed/29991676
http://dx.doi.org/10.1038/s41467-018-05083-x

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