Benzo(a)pyrene in Cigarette Smoke Enhances HIV-1 Replication through NF-κB Activation via CYP-Mediated Oxidative Stress Pathway

Smoking aggravates HIV-1 pathogenesis and leads to decreased responses to antiretroviral therapy. In this study, we aim to find a molecular mechanism that would explain smoking-induced HIV-1 replication. Benzo(a)pyrene (BaP), a major carcinogen in cigarette, requires metabolic activation through cyt...

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Detalles Bibliográficos
Autores principales: Ranjit, Sabina, Sinha, Namita, Kodidela, Sunitha, Kumar, Santosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039513/
https://www.ncbi.nlm.nih.gov/pubmed/29991690
http://dx.doi.org/10.1038/s41598-018-28500-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039513/
https://www.ncbi.nlm.nih.gov/pubmed/29991690
http://dx.doi.org/10.1038/s41598-018-28500-z

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