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Synthesis of pentafluorosulfanyl (SF(5)) containing aromatic amino acids

Herein, a series of aromatic pentafluorosulfanyl (SF(5)) containing amino acids are reported. A Negishi cross-coupling strategy utilising a catalyst system of Pd(dba)(2) and SPhos afforded the aforementioned SF(5) amino acids in yields between 32% and 42%. Two dipeptides utilising both the amine and...

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Detalles Bibliográficos
Autores principales:	Grigolato, Lucas, Brittain, William D.G., Hudson, Alex S., Czyzewska, Maria M., Cobb, Steven L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Sequoia Sa 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039762/ https://www.ncbi.nlm.nih.gov/pubmed/30078911 http://dx.doi.org/10.1016/j.jfluchem.2018.06.006

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