Cargando…

Comparison of Glass Capillary Plates and Polyethylene Fiber Bundles as Phantoms to Assess the Quality of Diffusion Tensor Imaging

PURPOSE: The purpose of this study was to evaluate the suitability of two phantoms, one made of capillary plates and the other polyethylene fibers, for assessing the quality of diffusion tensor imaging (DTI). METHODS: The first phantom was a stack of glass capillary plates with many parallel micropo...

Descripción completa

Detalles Bibliográficos
Autores principales: Tachibana, Atsushi, Tachibana, Yasuhiko, Kershaw, Jeff, Sano, Hiromi, Fukushi, Masahiro, Obata, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Magnetic Resonance in Medicine 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039775/
https://www.ncbi.nlm.nih.gov/pubmed/29212957
http://dx.doi.org/10.2463/mrms.mp.2017-0079
_version_ 1783338742720757760
author Tachibana, Atsushi
Tachibana, Yasuhiko
Kershaw, Jeff
Sano, Hiromi
Fukushi, Masahiro
Obata, Takayuki
author_facet Tachibana, Atsushi
Tachibana, Yasuhiko
Kershaw, Jeff
Sano, Hiromi
Fukushi, Masahiro
Obata, Takayuki
author_sort Tachibana, Atsushi
collection PubMed
description PURPOSE: The purpose of this study was to evaluate the suitability of two phantoms, one made of capillary plates and the other polyethylene fibers, for assessing the quality of diffusion tensor imaging (DTI). METHODS: The first phantom was a stack of glass capillary plates with many parallel micropores (CP). The second phantom was a bundle of polyethylene fiber Dyneema held together with a thermal shrinkage tube (Dy). High resolution multi-shot echo planar imaging (EPI) DTI acquisitions were performed at b-values of 0 and 1000 s/mm(2) and diffusion-times (T(diff)) of 37.7 and 97.7 ms on a preclinical 7T MRI scanner. Thirty diffusion-encoding directions were used. The data were used to calculate the fractional anisotropy (FA), mean diffusivity (MD), and angular dispersion (AD). Further acquisitions were performed at b-values from 0 to 8000 s/mm(2) in 14 steps with the diffusion gradient applied parallel (axial) and perpendicular (radial) to the Z direction. On the other hand, the data acquired with a 3T MRI scanner were used to confirm that measurements on a clinical machine are consistent with the 7T MRI results. RESULTS: The dependence of FA, MD and AD on T(diff) was smaller for the Dy than for the CPs. The b-value-dependent signal attenuations in the axial direction at T(diff) = 37.7 and 97.7 ms were similar for both phantoms. In the radial direction, Dy demonstrated similar b-value attenuation to that of in vivo tissue for both T(diff)s, but the attenuation for the CPs was affected by the change in T(diff). Parameter estimates were similar for 3T and 7T MRI. CONCLUSION: The characteristics of the CP indicate that it can be used as a restricted-diffusion dominant phantom, while the characteristics of the Dy suggest that it can be used as a hindered-diffusion dominant phantom. Dy may be more suitable than CP for DTI quality control.
format Online
Article
Text
id pubmed-6039775
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Japanese Society for Magnetic Resonance in Medicine
record_format MEDLINE/PubMed
spelling pubmed-60397752018-07-20 Comparison of Glass Capillary Plates and Polyethylene Fiber Bundles as Phantoms to Assess the Quality of Diffusion Tensor Imaging Tachibana, Atsushi Tachibana, Yasuhiko Kershaw, Jeff Sano, Hiromi Fukushi, Masahiro Obata, Takayuki Magn Reson Med Sci Major Paper PURPOSE: The purpose of this study was to evaluate the suitability of two phantoms, one made of capillary plates and the other polyethylene fibers, for assessing the quality of diffusion tensor imaging (DTI). METHODS: The first phantom was a stack of glass capillary plates with many parallel micropores (CP). The second phantom was a bundle of polyethylene fiber Dyneema held together with a thermal shrinkage tube (Dy). High resolution multi-shot echo planar imaging (EPI) DTI acquisitions were performed at b-values of 0 and 1000 s/mm(2) and diffusion-times (T(diff)) of 37.7 and 97.7 ms on a preclinical 7T MRI scanner. Thirty diffusion-encoding directions were used. The data were used to calculate the fractional anisotropy (FA), mean diffusivity (MD), and angular dispersion (AD). Further acquisitions were performed at b-values from 0 to 8000 s/mm(2) in 14 steps with the diffusion gradient applied parallel (axial) and perpendicular (radial) to the Z direction. On the other hand, the data acquired with a 3T MRI scanner were used to confirm that measurements on a clinical machine are consistent with the 7T MRI results. RESULTS: The dependence of FA, MD and AD on T(diff) was smaller for the Dy than for the CPs. The b-value-dependent signal attenuations in the axial direction at T(diff) = 37.7 and 97.7 ms were similar for both phantoms. In the radial direction, Dy demonstrated similar b-value attenuation to that of in vivo tissue for both T(diff)s, but the attenuation for the CPs was affected by the change in T(diff). Parameter estimates were similar for 3T and 7T MRI. CONCLUSION: The characteristics of the CP indicate that it can be used as a restricted-diffusion dominant phantom, while the characteristics of the Dy suggest that it can be used as a hindered-diffusion dominant phantom. Dy may be more suitable than CP for DTI quality control. Japanese Society for Magnetic Resonance in Medicine 2017-12-05 /pmc/articles/PMC6039775/ /pubmed/29212957 http://dx.doi.org/10.2463/mrms.mp.2017-0079 Text en © 2017 Japanese Society for Magnetic Resonance in Medicine This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Major Paper
Tachibana, Atsushi
Tachibana, Yasuhiko
Kershaw, Jeff
Sano, Hiromi
Fukushi, Masahiro
Obata, Takayuki
Comparison of Glass Capillary Plates and Polyethylene Fiber Bundles as Phantoms to Assess the Quality of Diffusion Tensor Imaging
title Comparison of Glass Capillary Plates and Polyethylene Fiber Bundles as Phantoms to Assess the Quality of Diffusion Tensor Imaging
title_full Comparison of Glass Capillary Plates and Polyethylene Fiber Bundles as Phantoms to Assess the Quality of Diffusion Tensor Imaging
title_fullStr Comparison of Glass Capillary Plates and Polyethylene Fiber Bundles as Phantoms to Assess the Quality of Diffusion Tensor Imaging
title_full_unstemmed Comparison of Glass Capillary Plates and Polyethylene Fiber Bundles as Phantoms to Assess the Quality of Diffusion Tensor Imaging
title_short Comparison of Glass Capillary Plates and Polyethylene Fiber Bundles as Phantoms to Assess the Quality of Diffusion Tensor Imaging
title_sort comparison of glass capillary plates and polyethylene fiber bundles as phantoms to assess the quality of diffusion tensor imaging
topic Major Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039775/
https://www.ncbi.nlm.nih.gov/pubmed/29212957
http://dx.doi.org/10.2463/mrms.mp.2017-0079
work_keys_str_mv AT tachibanaatsushi comparisonofglasscapillaryplatesandpolyethylenefiberbundlesasphantomstoassessthequalityofdiffusiontensorimaging
AT tachibanayasuhiko comparisonofglasscapillaryplatesandpolyethylenefiberbundlesasphantomstoassessthequalityofdiffusiontensorimaging
AT kershawjeff comparisonofglasscapillaryplatesandpolyethylenefiberbundlesasphantomstoassessthequalityofdiffusiontensorimaging
AT sanohiromi comparisonofglasscapillaryplatesandpolyethylenefiberbundlesasphantomstoassessthequalityofdiffusiontensorimaging
AT fukushimasahiro comparisonofglasscapillaryplatesandpolyethylenefiberbundlesasphantomstoassessthequalityofdiffusiontensorimaging
AT obatatakayuki comparisonofglasscapillaryplatesandpolyethylenefiberbundlesasphantomstoassessthequalityofdiffusiontensorimaging