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The dynamic upper limit of human lifespan
We respond to claims by Dong et al. that human lifespan is limited below 125 years. Using the log-linear increase in mortality rates with age to predict the upper limits of human survival we find, in contrast to Dong et al., that the limit to human lifespan is historically flexible and increasing. T...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039923/ https://www.ncbi.nlm.nih.gov/pubmed/30026910 http://dx.doi.org/10.12688/f1000research.11438.2 |
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author | Newman, Saul Easteal, Simon |
author_facet | Newman, Saul Easteal, Simon |
author_sort | Newman, Saul |
collection | PubMed |
description | We respond to claims by Dong et al. that human lifespan is limited below 125 years. Using the log-linear increase in mortality rates with age to predict the upper limits of human survival we find, in contrast to Dong et al., that the limit to human lifespan is historically flexible and increasing. This discrepancy can be explained by Dong et al.’s use of data with variable sample sizes, age-biased rounding errors, and log(0) instead of log(1) values in linear regressions. Addressing these issues eliminates the proposed 125-year upper limit to human lifespan. |
format | Online Article Text |
id | pubmed-6039923 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | F1000 Research Limited |
record_format | MEDLINE/PubMed |
spelling | pubmed-60399232018-07-18 The dynamic upper limit of human lifespan Newman, Saul Easteal, Simon F1000Res Research Article We respond to claims by Dong et al. that human lifespan is limited below 125 years. Using the log-linear increase in mortality rates with age to predict the upper limits of human survival we find, in contrast to Dong et al., that the limit to human lifespan is historically flexible and increasing. This discrepancy can be explained by Dong et al.’s use of data with variable sample sizes, age-biased rounding errors, and log(0) instead of log(1) values in linear regressions. Addressing these issues eliminates the proposed 125-year upper limit to human lifespan. F1000 Research Limited 2017-06-09 /pmc/articles/PMC6039923/ /pubmed/30026910 http://dx.doi.org/10.12688/f1000research.11438.2 Text en Copyright: © 2017 Newman S and Easteal S http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Newman, Saul Easteal, Simon The dynamic upper limit of human lifespan |
title | The dynamic upper limit of human lifespan |
title_full | The dynamic upper limit of human lifespan |
title_fullStr | The dynamic upper limit of human lifespan |
title_full_unstemmed | The dynamic upper limit of human lifespan |
title_short | The dynamic upper limit of human lifespan |
title_sort | dynamic upper limit of human lifespan |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039923/ https://www.ncbi.nlm.nih.gov/pubmed/30026910 http://dx.doi.org/10.12688/f1000research.11438.2 |
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