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High monocyte to lymphocyte ratio is associated with impaired protection after subcutaneous administration of BCG in a mouse model of tuberculosis

Background: The only available tuberculosis (TB) vaccine, Bacillus Calmette-Guérin (BCG), has variable efficacy. New vaccines are therefore urgently needed. Why BCG fails is incompletely understood, and the tools used for early assessment of new vaccine candidates do not account for BCG variability....

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Detalles Bibliográficos
Autores principales:	Zelmer, Andrea, Stockdale, Lisa, Prabowo, Satria A., Cia, Felipe, Spink, Natasha, Gibb, Matthew, Eddaoudi, Ayad, Fletcher, Helen A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	F1000 Research Limited 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039926/ https://www.ncbi.nlm.nih.gov/pubmed/30026926 http://dx.doi.org/10.12688/f1000research.14239.2

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