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Optoacoustic signal excitation with a tone-burst of short pulses

Individual light pulses with durations in the nanosecond range are most often employed in biomedical optoacoustic imaging. In this excitation regime, ultra-wideband acoustic responses are generated from tissues that cannot be efficiently captured with ultrasound transducers having a limited detectio...

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Detalles Bibliográficos
Autores principales: Deán-Ben, X.L., Razansky, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039968/
https://www.ncbi.nlm.nih.gov/pubmed/30003040
http://dx.doi.org/10.1016/j.pacs.2018.06.001
Descripción
Sumario:Individual light pulses with durations in the nanosecond range are most often employed in biomedical optoacoustic imaging. In this excitation regime, ultra-wideband acoustic responses are generated from tissues that cannot be efficiently captured with ultrasound transducers having a limited detection bandwidth. Here, we analyse a narrowband optoacoustic signal excitation mechanism consisting of a tone-burst of multiple equally-delayed pulses. The signal generation efficiency of single-pulse versus tone-burst excitation is compared for normal light exposure levels in the linear optoacoustic signal generation regime as well as when considering non-linearities associated with temperature increase or absorption saturation. The signal-to-noise ratio of the excited signals is also experimentally compared using a highly-absorbing ink phantom.