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Corneal integrity and thickness of central fovea after phacoemulsification surgery in diabetic and nondiabetic cataract patients
INTRODUCTION: Here we intended to investigate the changes in corneal endothelial cells and foveal thickness after phacoemulsification surgery on the eyes of diabetic and non-diabetic cataract patients. MATERIAL AND METHODS: A total of 120 cataract patients who were scheduled for phacoemulsification...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040132/ https://www.ncbi.nlm.nih.gov/pubmed/30002699 http://dx.doi.org/10.5114/aoms.2016.64036 |
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author | Chen, Zhuo Song, Fanqian Sun, Liyao Zhao, Chuchu Gao, Ningning Liu, Ping Ge, Hongyan |
author_facet | Chen, Zhuo Song, Fanqian Sun, Liyao Zhao, Chuchu Gao, Ningning Liu, Ping Ge, Hongyan |
author_sort | Chen, Zhuo |
collection | PubMed |
description | INTRODUCTION: Here we intended to investigate the changes in corneal endothelial cells and foveal thickness after phacoemulsification surgery on the eyes of diabetic and non-diabetic cataract patients. MATERIAL AND METHODS: A total of 120 cataract patients who were scheduled for phacoemulsification surgery and intraocular lens implantation were recruited and divided into 2 categories according to the diagnosis of diabetes mellitus. Changes in integrity, endothelial cell density (ECD), coefficient of variation (CV), percentage of hexagonal cells (PHC), central corneal thickness (CCT), and central foveal thickness (CFT) were all recorded at preoperative day 1 and postoperative day 3, 1 week, 1 month, 3 months and 6 months. RESULTS: None of the recorded variables showed any difference between the nondiabetic and diabetic groups before surgery (p > 0.05). During the postoperative 6 months, ECD and PHC decreased and CV increased in both groups (all p(time) < 0.05), whereas CCT and CFT fluctuated in both groups significantly (both p(time) < 0.05), with their individual peaks at postoperative 1 week in the diabetic group. The groups differed significantly in ECD, PHC, and CV at each time point postoperatively (all p(group) < 0.05). Furthermore, the diabetic group had improved CFT during the postoperative 1 month and higher CCT during the 6 months postoperatively than the nondiabetic group (all p(group) < 0.05). The time and group interactions were significant for ECD, CV, PHC, CCT and CFT (all p(group × time) < 0.05). CONCLUSIONS: The diabetic group had more changes in corneal endothelial cells and foveal thickness than the nondiabetic group postoperatively. |
format | Online Article Text |
id | pubmed-6040132 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Termedia Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-60401322018-07-12 Corneal integrity and thickness of central fovea after phacoemulsification surgery in diabetic and nondiabetic cataract patients Chen, Zhuo Song, Fanqian Sun, Liyao Zhao, Chuchu Gao, Ningning Liu, Ping Ge, Hongyan Arch Med Sci Clinical Research INTRODUCTION: Here we intended to investigate the changes in corneal endothelial cells and foveal thickness after phacoemulsification surgery on the eyes of diabetic and non-diabetic cataract patients. MATERIAL AND METHODS: A total of 120 cataract patients who were scheduled for phacoemulsification surgery and intraocular lens implantation were recruited and divided into 2 categories according to the diagnosis of diabetes mellitus. Changes in integrity, endothelial cell density (ECD), coefficient of variation (CV), percentage of hexagonal cells (PHC), central corneal thickness (CCT), and central foveal thickness (CFT) were all recorded at preoperative day 1 and postoperative day 3, 1 week, 1 month, 3 months and 6 months. RESULTS: None of the recorded variables showed any difference between the nondiabetic and diabetic groups before surgery (p > 0.05). During the postoperative 6 months, ECD and PHC decreased and CV increased in both groups (all p(time) < 0.05), whereas CCT and CFT fluctuated in both groups significantly (both p(time) < 0.05), with their individual peaks at postoperative 1 week in the diabetic group. The groups differed significantly in ECD, PHC, and CV at each time point postoperatively (all p(group) < 0.05). Furthermore, the diabetic group had improved CFT during the postoperative 1 month and higher CCT during the 6 months postoperatively than the nondiabetic group (all p(group) < 0.05). The time and group interactions were significant for ECD, CV, PHC, CCT and CFT (all p(group × time) < 0.05). CONCLUSIONS: The diabetic group had more changes in corneal endothelial cells and foveal thickness than the nondiabetic group postoperatively. Termedia Publishing House 2016-11-29 2018-06 /pmc/articles/PMC6040132/ /pubmed/30002699 http://dx.doi.org/10.5114/aoms.2016.64036 Text en Copyright: © 2016 Termedia & Banach http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license. |
spellingShingle | Clinical Research Chen, Zhuo Song, Fanqian Sun, Liyao Zhao, Chuchu Gao, Ningning Liu, Ping Ge, Hongyan Corneal integrity and thickness of central fovea after phacoemulsification surgery in diabetic and nondiabetic cataract patients |
title | Corneal integrity and thickness of central fovea after phacoemulsification surgery in diabetic and nondiabetic cataract patients |
title_full | Corneal integrity and thickness of central fovea after phacoemulsification surgery in diabetic and nondiabetic cataract patients |
title_fullStr | Corneal integrity and thickness of central fovea after phacoemulsification surgery in diabetic and nondiabetic cataract patients |
title_full_unstemmed | Corneal integrity and thickness of central fovea after phacoemulsification surgery in diabetic and nondiabetic cataract patients |
title_short | Corneal integrity and thickness of central fovea after phacoemulsification surgery in diabetic and nondiabetic cataract patients |
title_sort | corneal integrity and thickness of central fovea after phacoemulsification surgery in diabetic and nondiabetic cataract patients |
topic | Clinical Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040132/ https://www.ncbi.nlm.nih.gov/pubmed/30002699 http://dx.doi.org/10.5114/aoms.2016.64036 |
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