Double Knockout of Peroxiredoxin 4 (Prdx4) and Superoxide Dismutase 1 (Sod1) in Mice Results in Severe Liver Failure

Mice that are deficient in superoxide dismutase 1 (Sod1), an antioxidative enzyme, are susceptible to developing liver steatosis. Peroxiredoxin 4 (Prdx4) catalyzes disulfide bond formation in proteins via the action of hydrogen peroxide and hence decreases oxidative stress and supports oxidative pro...

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Detalles Bibliográficos
Autores principales: Homma, Takujiro, Kurahashi, Toshihiro, Lee, Jaeyong, Nabeshima, Atsunori, Yamada, Sohsuke, Fujii, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040270/
https://www.ncbi.nlm.nih.gov/pubmed/30050648
http://dx.doi.org/10.1155/2018/2812904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040270/
https://www.ncbi.nlm.nih.gov/pubmed/30050648
http://dx.doi.org/10.1155/2018/2812904

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