Cargando…

Double Knockout of Peroxiredoxin 4 (Prdx4) and Superoxide Dismutase 1 (Sod1) in Mice Results in Severe Liver Failure

Mice that are deficient in superoxide dismutase 1 (Sod1), an antioxidative enzyme, are susceptible to developing liver steatosis. Peroxiredoxin 4 (Prdx4) catalyzes disulfide bond formation in proteins via the action of hydrogen peroxide and hence decreases oxidative stress and supports oxidative pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Homma, Takujiro, Kurahashi, Toshihiro, Lee, Jaeyong, Nabeshima, Atsunori, Yamada, Sohsuke, Fujii, Junichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040270/ https://www.ncbi.nlm.nih.gov/pubmed/30050648 http://dx.doi.org/10.1155/2018/2812904

Ejemplares similares

Testis-specific peroxiredoxin 4 variant is not absolutely required for spermatogenesis and fertility in mice
por: Homma, Takujiro, et al.
Publicado: (2020)

Protective Effects of Peroxiredoxin 4 (PRDX4) on Cholestatic Liver Injury
por: Zhang, Jing, et al.
Publicado: (2018)

Superoxide Dismutases (SODs) and SOD Mimetics
por: Borgstahl, Gloria E. O., et al.
Publicado: (2018)

Superoxide Radicals in the Execution of Cell Death
por: Fujii, Junichi, et al.
Publicado: (2022)

Nitric oxide produced by NOS2 copes with the cytotoxic effects of superoxide in macrophages
por: Kobayashi, Sho, et al.
Publicado: (2021)

Superoxide Dismutase Gene (SOD1, SOD2, and SOD3) Polymorphisms and Antituberculosis Drug-induced Hepatitis
por: Kim, Sang-Hoon, et al.
Publicado: (2015)

The activity of superoxide dismutases (SODs) at the early stages of wheat deetiolation
por: Leonowicz, Gracjana, et al.
Publicado: (2018)

Protective role of testis-specific peroxiredoxin 4 against cellular oxidative stress
por: Tasaki, Eisuke, et al.
Publicado: (2017)

Oxidative Stress Induced Age Dependent Meibomian Gland Dysfunction in Cu, Zn-Superoxide Dismutase-1 (Sod1) Knockout Mice
por: Ibrahim, Osama M. A., et al.
Publicado: (2014)

Superoxide dismutase SOD-1 modulates C. elegans pathogen avoidance behavior
por: Horspool, Alexander M., et al.
Publicado: (2017)

A lecithinized superoxide dismutase (PC-SOD) improves ulcerative colitis
por: Suzuki, Y, et al.
Publicado: (2008)

Human extracellular superoxide dismutase (EC-SOD) expression in transgenic chicken
por: Byun, Sung June, et al.
Publicado: (2013)

The Effect of Extracellular Superoxide Dismutase (SOD3) Gene in Lung Cancer
por: Zhang, Yundi, et al.
Publicado: (2022)

The effects of 3% diquafosol sodium application on the tear functions and ocular surface of the Cu,Zn-superoxide dismutase-1 (Sod1)–knockout mice
por: Kojima, Takashi, et al.
Publicado: (2014)

Deletion of the Mitochondrial Superoxide Dismutase sod-2 Extends Lifespan in Caenorhabditis elegans
por: Van Raamsdonk, Jeremy M., et al.
Publicado: (2009)

Neonatal Extracellular Superoxide Dismutase Knockout Mice Increase Total Superoxide Dismutase Activity and VEGF Expression after Chronic Hyperoxia
por: Mathias, Maxwell, et al.
Publicado: (2021)

Overexpression of Peroxiredoxin 4 Affects Intestinal Function in a Dietary Mouse Model of Nonalcoholic Fatty Liver Disease
por: Nawata, Aya, et al.
Publicado: (2016)

Alterations in Concentration/Activity of Superoxide Dismutases in Context of Obesity and Selected Single Nucleotide Polymorphisms in Genes: SOD1, SOD2, SOD3
por: Lewandowski, Łukasz, et al.
Publicado: (2020)

Ceruloplasmin and superoxide dismutase (SOD1) in heterozygotes for Wilson disease: A case control study
por: Tórsdóttir, Gudlaug, et al.
Publicado: (2009)

Cytosolic Superoxide Dismutase (SOD1) Is Critical for Tolerating the Oxidative Stress of Zinc Deficiency in Yeast
por: Wu, Chang-Yi, et al.
Publicado: (2009)

Conformational dynamics of superoxide dismutase (SOD1) in osmolytes: a molecular dynamics simulation study
por: Jahan, Ishrat, et al.
Publicado: (2020)

Peroxiredoxin 1 (PRDX1) Suppresses Progressions and Metastasis of Osteosarcoma and Fibrosarcoma of Bone
por: Wang, Yongxiang, et al.
Publicado: (2018)

Superoxide Dismutases and Superoxide Reductases
por: Sheng, Yuewei, et al.
Publicado: (2014)

The subunit composition of human extracellular superoxide dismutase (EC-SOD) regulate enzymatic activity
por: Petersen, Steen V, et al.
Publicado: (2007)

Radioprotective and tumor antiangiogenic effect of the novel synthetic superoxide dismutase (SOD) mimetic compounds
por: Vujaskovic, Z, et al.
Publicado: (2001)

Formation of High-Order Oligomers by a Hyperthemostable Fe-Superoxide Dismutase (tcSOD)
por: Wang, Sha, et al.
Publicado: (2014)

Immunohistochemical assessment of mitochondrial superoxide dismutase (MnSOD) in colorectal premalignant and malignant lesions
por: Piecuch, Adam, et al.
Publicado: (2016)

Genome-Wide Identification, Characterization, and Expression Analysis of the Grapevine Superoxide Dismutase (SOD) Family
por: Hu, Xiaoxuan, et al.
Publicado: (2019)

Genome-wide characterization and expression analyses of superoxide dismutase (SOD) genes in Gossypium hirsutum
por: Wang, Wei, et al.
Publicado: (2017)

The superoxide dismutase (SOD) genes family mediates the response of Nilaparvata lugens to jinggangmycin and sugar
por: Sheraz, Ahmad, et al.
Publicado: (2023)

Superoxide Dismutases, SOD1 and SOD2, Play a Distinct Role in the Fat Body during Pupation in Silkworm Bombyx mori
por: Nojima, Yosui, et al.
Publicado: (2015)

Identification of biomarkers for the antiangiogenic and antitumour activity of the superoxide dismutase 1 (SOD1) inhibitor tetrathiomolybdate (ATN-224)
por: Doñate, F, et al.
Publicado: (2008)

Quantifying the Interaction between Copper-Zinc Superoxide Dismutase (Sod1) and its Copper Chaperone (Ccs1)
por: Boyd, Stefanie D, et al.
Publicado: (2018)

Superoxide Dismutase 1 Nanoparticles (Nano-SOD1) as a Potential Drug for the Treatment of Inflammatory Eye Diseases
por: Vaneev, Alexander N., et al.
Publicado: (2021)

Characteristics of Skeletal Muscle Fibers of SOD1 Knockout Mice
por: Nagahisa, Hiroshi, et al.
Publicado: (2016)

The effects of superoxide dismutase knockout on the oxidative stress parameters and survival of mouse erythrocyt
por: Grzelak, Agnieszka, et al.
Publicado: (2008)

Superoxide Dismutase (SOD) Enzyme Activity Assay in Fasciola spp. Parasites and Liver Tissue Extract
por: Assady, M, et al.
Publicado: (2011)

Superoxide dismutase SodB is a protective antigen against Campylobacter jejuni colonisation in chickens
por: Chintoan-Uta, Cosmin, et al.
Publicado: (2015)

Effects of salinity change on two superoxide dismutases (SODs) in juvenile marbled eel Anguilla marmorata
por: Wang, Li, et al.
Publicado: (2016)

The Paradoxical Leishmanicidal Effects of Superoxide Dismutase (SOD)-Mimetic Tempol in Leishmania braziliensis Infection in vitro
por: Oliveira, Laíse B., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_no6eje1a6mov3tqbev9fgpqvun